Does sudafed wake you up

fexofenadine / pseudoephedrine. Generic Allegra-D. Used for Nasal Congestion, Allergic Rhinitis. Allegra-D (fexofenadine / pseudoephedrine) is a combination medication containing fexofenadine and pseudoephedrine. The two medications work together to relieve allergies and congestion without causing daytime sleepiness, but can keep you up at night.

Sep 17, 2023 · Decongestant medications, such as phenylephrine (Sudafed PE Congestion) and pseudoephedrine (Sudafed), can help dry out mucus. However, although these medications work for many people, they may ... As mentioned earlier, taking Sudafed and DayQuil together can increase your risk of side effects. Some of the common side effects of Sudafed include: Dizziness. Nervousness. Restlessness. Increased blood pressure. Difficulty sleeping. The common side effects of DayQuil include the following: Dizziness.There are certain meds you can get, literally, over the counter without a prescription. Sudafed is one. Due to it being an ingredient in the production of methamphetamine, you have to show your ID, and they log your purchase; you can only get a certain amount over a certain amount of time.Mucinex is a brand (trade) name for guaifenesin. Mucinex (guaifenesin) acts indirectly on the gastrointestinal vagal nerves which triggers reflex secretion from submucosal glands and goblet cells, increasing the water content of mucus, making it easier for it to be coughed out. Mucinex also affects the secretion of mucus from goblet and …3. Drink a big glass of water. Going 8 hours without drinking water (while you're asleep) is enough time for your body to get a little dehydrated, which can make you feel sleepy. Wake up to a big glass of cool water to start your day off right. You'll feel more alert within minutes. [3]The answer is yes. According to studies, the combination of caffeine with acetaminophen can help to enhance the pain-relieving and fever-reducing effects of the latter. In other words, drinking coffee while taking DayQuil can be good for your body. Just try not to drink past lunchtime to avoid nighttime sleep problems.You may also be wondering if this item is eligible or ineligible for reimbursement with your HSA, flexible spending account (FSA), or health reimbursement arrangement (HRA). Yes, you can pay for Sudafed with an HSA, FSA, or HRA. Look up another expense 🔎.Jan 2, 2019 · Answer. Nasal congestion can certainly make it difficult to get a good night's sleep. Worse still, it tends to become more severe at bedtime. Unfortunately, oral nasal decongestants, such a Sudafed (pseudoephedrine) and Sudafed PE (phenylephrine), have stimulating effects for many individuals, and therefore may not be an option for you at bedtime.

Common decongestants include the following: Sudafed ( Pseudoephedrine ) Sudafed PE ( Phenylephrine ) Afrin ( Oxymetazoline ) Nasal sprays work faster than oral decongestants. Don't use them for longer than recommended, though. They can irritate your nasal passages and make congestion worse.Consuming soda too close to bedtime may lead to disrupted sleep patterns. Artificial carbonation, caffeine, and sugar can interfere with your ability to fall asleep and stay asleep. In the evening, substitute soda with naturally flavored water to prevent sleep issues. Whether you know them as sodas, pop, coke, or by another name, carbonated ...Nasal Decongestant. Nasal decongestants are a type of medicine that helps provide relief for stuffy, congested noses (nasal congestion). They work by narrowing and reducing the swelling in the blood vessels and tissues in your nose. Nasal decongestants come as pills, liquids, drops and nasal sprays. Nasal spray is one type of nasal decongestant.Nervousness. Hypertension. Atrial fibrillation. Myocardial infarction. Ventricular premature beats. Ischemic colitis. The incidence of these side effects will be increased if Sudafed and Benadryl are taken together or overdosed. Therefore, patients should take only one of these products for their cold and runny nose symptoms.Phlegm is a specific form of mucus produced in the lungs and respiratory tracts. It's similar to the mucus in your throat and nose but thicker. Both mucus and phlegm help carry dirt, debris and bacteria away from the nose and lungs to try and prevent illnesses. But too much mucus in one area can create discomfort and other problems.Mar 21, 2024 · A dangerous drug interaction could occur, leading to serious side effects. Do not use Sudafed if you are allergic to pseudoephedrine or to other decongestants, diet pills, stimulants, or ADHD medications. Ask a doctor or pharmacist if it is safe for you to take Sudafed if you have: heart disease or high blood pressure; diabetes; or. a thyroid ... pseudoephedrine lisdexamfetamine. Applies to: Sudafed 12-Hour (pseudoephedrine) and Vyvanse (lisdexamfetamine) Both pseudoephedrine and lisdexamfetamine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood ...The main function of a nasal decongestant is to reduce the congestion, or stuffiness you feel in your nose when you're sick. 1 When you have a cold or allergies, your immune system responds by sending a flood of white blood cells to your nasal area to combat the invading virus or allergen. 2 These cells produce a range of inflammatory substances to fight off the invaders - but these ...

There are 10,737 people reported to have side effects when taking Sudafed. Among them, 172 (1.6%) have dehydration. These people tend to be female, 60+ old, have been taking the drug for < 1 month, also take medication Effexor, and have Stress and anxietyJan 29, 2024 · Yes, you can take Sudafed with NyQuil, but both medications should have a bit of a dosing gap. Sudafed is a decongestant containing pseudoephedrine, whereas NyQuil is a multi-ingredient medication containing acetaminophen, dextromethorphan and doxylamine. NyQuil does not work for nasal congestion (1,2). Sudafed is used to provide temporary ... 1. How it works. Pseudoephedrine is a decongestant that constricts (shrinks) dilated blood vessels within the nose, relieving congestion. It causes vasoconstriction by stimulating primarily alpha-adrenergic receptors. It also has weak activity at beta-adrenergic receptors.Yes, you can take Sudafed with NyQuil, but both medications should have a bit of a dosing gap. Sudafed is a decongestant containing pseudoephedrine, whereas NyQuil is a multi-ingredient medication containing acetaminophen, dextromethorphan and doxylamine. NyQuil does not work for nasal congestion (1,2). Sudafed is used to provide temporary ...

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Don't: Take a Hot Bath. It's true that a warm soak can help you fall asleep, but not if you're climbing out of the water immediately before climbing into bed. Here's why: Your body temperature dips at night, starting at around two hours before sleep. A hot bath causes your temperature to rise and then cool down afterward, which will help you relax.3. Do not double up if you miss a dose. If you forget to take your Singulair dose, skip the one you forgot and take the next dose at your regular time. Don't double up on your Singulair dose. Doing so can raise your risk of side effects without any extra benefits. 4. Let your pharmacist know about other medications and supplements you're takingDayQuil replaces the Pseudoephedrine for Phenylephrine, another decongestant, that is less drowsy. Bottom line, no matter how extreme the packaging, no matter how the description includes "Extreme Severe Cold Formula", it's just a combination of medicines that reduce symptoms.Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose). Sudafed PE Sinus & Allergy is a combination medicine used to treat symptoms of the common cold or seasonal allergies, including sneezing, runny or stuffy nose, and itchy, watery eyes.It is generally considered safe to use sudafed and zoloft but a few interactions are also reported. It is suspected that your antidepressant might cause your body to process sudafed more slowly. In addition, both medications can increase the level of serotonin. So, the concomitant use of zoloft and sudafed may increase the risk of serotonin ...A tear duct infection. Dacryocystitis is an infection of the tear ducts that can happen when (you guessed it) your bacterial sinus infection travels toward your eyes. Symptoms include eye pain ...

Alcohol can increase the nervous system side effects of zolpidem such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Taking zolpidem with food may delay the onset of sleep. For faster sleep onset, zolpidem should not be taken with or immediately after a meal.Answer. Yes, you can safely take Mucinex (guaifenesin) at night. It should not cause any problems sleeping and can help to clear up symptoms of chest congestion and excess mucus.. When To Take Mucinex. Guaifenesin, the active ingredient in Mucinex, is available in both 'extended-release' and 'immediate-release' dosage forms.Taking higher doses can put you at higher risk for negative side effects, Dr. Tallavajhula says, including dry mouth, dizziness and daytime grogginess. 3. You Could Have Rebound Insomnia. If you take Zzzquil for a while and then stop suddenly, your sleep problems will likely come back even worse than before, notes the Cleveland Clinic.It can cause symptoms like coughing, wheezing, chest congestion, and difficulty breathing. While there is no cure for bronchitis, medications like Sudafed can help alleviate its symptoms. Sudafed contains an active ingredient called pseudoephedrine, which is a decongestant. Decongestants work by constricting the blood vessels in the nasal ...How to use Sudafed PE Day And Night 10 Mg (Day)/25 Mg-10 (Nt) Tablets Oral Decongestants. Take this medication by mouth as directed by your doctor. If you are self-treating, follow all directions ...severe dizziness or nervousness; sleep problems (insomnia); or. increased blood pressure --severe headache, blurred vision, pounding in your neck or ears. flushing (warmth, redness, or tingly ...It is generally considered safe to use sudafed and zoloft but a few interactions are also reported. It is suspected that your antidepressant might cause your body to process sudafed more slowly. In addition, both medications can increase the level of serotonin. So, the concomitant use of zoloft and sudafed may increase the risk of serotonin ...Here are things you can do to relieve sinus congestion and related ear congestion: Take a nasal decongestant for up to 3 days. Blow your nose gently. Use a nasal rinse or nasal irrigation system ...Yes, Sudafed (pseudoephedrine), can safely be taken with Aleve (naproxen). There is no drug interaction between the two. In fact, these two drugs are available together in combination in a single product, Aleve-D Sinus & Cold. It's not clear in your question if you are referring to Sudafed, which contains pseudoephedrine, or Sudafed PE, which ...Sudafed is a decongestant. It narrows the blood vessels in the nose. By narrowing, the nose doesn't get as stuffy nor does it drip so much. If you have an allergy to a bee sting, you will know quickly and most likely will consider an ER immediately if you don't have a epi-pen. If you have a slight reaction, use the Benadryl at 50mg.

Sudafed (pseudoephedrine) is a nasal decongestant used to relieve allergy and common cold symptoms like stuffy nose and sinuses. Common side effects of Sudafed include tremor, restlessness, insomnia, nausea, vomiting, and nervousness. Serious side effects of Sudafed include high blood pressure, heart attack, abnormal heartbeats, and ischemic colitis. Consult your doctor before taking Sudafed ...

Each extended-release decongestant caplet contains 120 mg of pseudoephedrine HCl to provide 12 hours of powerful and non-drowsy congestion relief. This maximum strength formula temporarily relieves sinus congestion, sinus pressure, and nasal congestion caused by the common cold and allergies. From the #1 pharmacist recommended brand among oral ...The recommended dose of Sudafed Sinus + Pain Relief Day & Night for adults and children over 12 years is. Day time: 2 Day tablets in the morning and 2 tablets in the afternoon, as necessary. Night ... Check if it's non-allergic rhinitis. The most common symptoms of non-allergic rhinitis are: a blocked or runny nose. sneezing. an itchy nose. a reduced sense of smell. Sometimes non-allergic rhinitis can also cause a crust to form inside the nose. This may have a bad smell and bleed if you try to remove it. Effectiveness. Ease of Use. Satisfaction. After taking one dose of the Sudafed 24 it started to help me but it only lasted 8 hours. So I waited a full 24 hours before I took a second dose and it made me feel jittery and my heart was racing. Tried to eat and drink something but it didn't help.2) If possible, take Sudafed after nursing or pumping. You can feed the milk you pump unless adverse side effects are noted. 3) Pay attention to your baby for any side effects. If you notice anything that concerns you, contact a medical professional immediately. 4) Be sure to stay hydrated while taking Sudafed as it can cause dehydration.Sudafed is a nasal decongestant. It primarily contains the ingredient pseudoephedrine. Mucinex is a chest decongestant. It primarily uses the ingredient guaifenesin. On the market, you may see different brands using guaifenesin, and other brands using pseudoephedrine. You should check with your pharmacist, so they can advise you on the right ...Applies to: ciprofloxacin and Sudafed 12 Hour Pressure+Pain (naproxen / pseudoephedrine) Ciprofloxacin may rarely cause central nervous system side effects such as tremors, involuntary muscle movements, anxiety, confusion, depression, hallucinations or seizures, and combining it with other medications that can also affect the central nervous ...

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Don't: Take a Hot Bath. It's true that a warm soak can help you fall asleep, but not if you're climbing out of the water immediately before climbing into bed. Here's why: Your body temperature dips at night, starting at around two hours before sleep. A hot bath causes your temperature to rise and then cool down afterward, which will help you relax.Limit your use of caffeine (for example, tea, coffee, cola) and chocolate. Use with Sudafed 12 Hour (pseudoephedrine extended-release tablets (12 hour)) may cause nervousness, shakiness, and a fast heartbeat. Different forms of Sudafed 12 Hour (pseudoephedrine extended-release tablets (12 hour)) may be for use in different ages of children.Natural Wake-Up Techniques: Oxygen Administration: Supplemental oxygen is administered to promote increased oxygen saturation levels by accelerating the removal of anesthetic gases. Temperature Regulation: The monitoring and maintaining body temperature will enable a controlled and gradual emergence from anesthesia.Yes, you can take Sudafed with NyQuil, but both medications should have a bit of a dosing gap. Sudafed is a decongestant containing pseudoephedrine, whereas NyQuil is a multi-ingredient medication containing acetaminophen, dextromethorphan and doxylamine. NyQuil does not work for nasal congestion (1,2). Sudafed is used to provide temporary ...The Spiritual Significance of Waking Up at 4am. Waking up at 4am is often associated with the idea of the “hour of the wolf.”. This term refers to the time of night when people are most vulnerable and when the devil is said to be the most active. However, in the Bible, waking up at 4am has a more positive connotation.Sudafed Congestion Interactions. There are 181 drugs known to interact with Sudafed Congestion (pseudoephedrine), along with 6 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 14 are major, 162 are moderate, and 5 are minor.It doesn't get you 'high' per se, but pseudoephedrine (and it's cousin ephedrine) are no bullshit stimulants. If you take too much you will be tweaking for awhile. I am a very experienced drug user overall, but i don't use a lot of stims and I have a sensitivity to them. I took pseudoephedrine a few weeks ago (just one, the recommended dose ...Find patient medical information for Sudafed PE Head Congestion-Flu oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.She also cautions that you must determine the reason for the wake-up calls before you can start ignoring your dog. "For example, if your dog wakes you up because they have to do their business ...Fainting, blackouts and anxiety. Yes, this is typically referred to as a panic attack, and these can be fairly common on undiagnosed celiacs who still eat gluten. I had this symptom for years before being diagnosed. 10 hours ago - Scott Adams replied to Painful5 's topic in Related Issues & Disorders. 1. ….

A Common Cold. With more than 1 billion colds in the United States each year, it's likely your head congestion is caused by the common cold. When you catch a cold, a virus infects your nose and throat, resulting in head cold symptoms like a runny nose, sneezing, coughing and headaches. This virus causes your nose to make thick, clear mucus ...Sudafed: takes at least an hour to kick in, maybe two; but once it does, I literally forget about food for the rest of the day. It's much more of a slow burn than Bronkaid, and it lasts all day with no jitters. I have to have a glass of wine before bed, though, or I'll never get to sleep.sore throat. sneezing. runny nose. congestion. fatigue. aches. Generally, these symptoms are most severe in the middle of a cold, around days 3-5. By the last days of a cold, most symptoms will ...Sudafed Congestion Pill Images. Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. Multi-ingredient medications may also be listed when applicable.High levels of potassium can cause weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs. Call your doctor at once if you have any of these symptoms. In some patients grapefruits and grapefruit juice may decrease the efficacy of losartan. Grapefruits and grapefruit juice should be avoided if ...It can cause symptoms like coughing, wheezing, chest congestion, and difficulty breathing. While there is no cure for bronchitis, medications like Sudafed can help alleviate its symptoms. Sudafed contains an active ingredient called pseudoephedrine, which is a decongestant. Decongestants work by constricting the blood vessels in the nasal ...Saline nasal flushes. You'll use a device like a Neti pot to pour a solution into one nostril and let it drain out the other. It can help relieve congestion, but the effects may not last long ...i can sleep because my nose is congestion and i use sudafed spray but work for some time and they wake me up again .thanks for you help.sincerely ***** ***** Submitted: 14 years ago. Category: MedicalGoodRx Health. When you have a stuffy nose and go to the pharmacy looking for relief, you encounter a variety of decongestants designed to help you breathe freely again. One of them is Sudafed …Limit your use of caffeine (for example, tea, coffee, cola) and chocolate. Use with this drug may cause nervousness, shakiness, and a fast heartbeat. Different forms of this drug may be for use in different ages of children. Talk with the doctor before giving this drug to a child. Does sudafed wake you up, Does Sudafed help with erections? When you have a full erection, no fresh blood flows into your penis. This means that your penis isn't getting oxygen, which can damage the tissue and lead to permanent erectile dysfunction (ED). If you have priapism, taking pseudoephedrine HCl (Sudafed ) can help., Natural Wake-Up Techniques: Oxygen Administration: Supplemental oxygen is administered to promote increased oxygen saturation levels by accelerating the removal of anesthetic gases. Temperature Regulation: The monitoring and maintaining body temperature will enable a controlled and gradual emergence from anesthesia., In one often-cited study, classic chicken soup lowered white blood cells ( neutrophils) in the upper airways of people with colds, which seemed to help with symptoms. Experts say that any hot liquid (not just soup) can thin mucus and may help with postnasal drip. Home Remedies for Postnasal Drip., Here's what might be going on if you're shaking after waking up — and what you can do about it. 1. Your Blood Sugar Is Low. Low blood sugar could be the culprit for your morning shakes (or shaking when you wake up from a nap). "It is possible to wake up feeling like you are having tremors if your blood sugar is low," says Margot Savoy, MD ..., Answers. IN. Inactive 29 Aug 2012. The half life I believe might be six to twelve hours. Regards, pledge. +0. MA. Marvell 29 July 2012. Which formulation did you take ... the 12 hour or the 24 hour Sudafed?, acetaminophen food. Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea ..., Relieve your symptoms with SUDAFED ®. If you're suffering from hay fever, congestion may occur, making it harder to breathe through your nose SUDAFED ® Congestion Relief Nasal Spray helps to clear the stuffy, blocked up feeling in your nose caused by allergies like hay fever. It also contains a soothing moisturising agent to moisturise the ..., Claritin-D may have different side effects than Claritin because pseudoephedrine is a stimulant decongestant. Claritin is a second-generation antihistamine that can cause drowsiness. What causes Sudafed to wake you up? Sudafed’s chemical formula is similar to adrenaline, which acts as a stimulant in addition to acting as a natural decongestant. , Diphenhydramine can have side effects, including nervousness, dry nose, mouth, and throat, dizziness, headache, nausea, and loss of appetite. In addition to these side effects, several other downsides of taking Benadryl are important to keep in mind. Reduced sleep quality: Benadryl may make people sleepy, but studies have not found …, Catarrh is a build-up of mucus in an airway or cavity in your body, such as the sinuses, nose and throat 1. It’s often temporary and can be caused by a cold, infection, nasal polyps, hay fever and other allergies 2. Post nasal drip is commonly associated with catarrh. This is when excess mucus drips from the back of the nose into the throat., Yes I take it daily, not sure if that's healthy. My doctor told me that Sudafed raises your blood pressure and should not be taken long-term. yeah, i do. it does help me as well. Assuming you are referring to Sudafed containing ( Pseudoephedrine) it's to be expected as it's a stimulant., The best way to eliminate alarm clocks from your life and transition into a less stressful natural sleep cycle is to go to bed earlier. If you can wake up before an alarm clock would ring and ..., Sudafed is a nasal decongestant. It primarily contains the ingredient pseudoephedrine. Mucinex is a chest decongestant. It primarily uses the ingredient guaifenesin. On the market, you may see different brands using guaifenesin, and other brands using pseudoephedrine. You should check with your pharmacist, so they can advise you on the right ..., Soon. I have a friend who did this, she took it according to the package instructions (it was like 2 capsules, every 6 hours). And it only took 2 days (8 doses) for her to notice a huge decline. She never pumped to help the engorgement, but she did hand express a little here and there just to take the edge off., Effectiveness. Ease of Use. Satisfaction. After taking one dose of the Sudafed 24 it started to help me but it only lasted 8 hours. So I waited a full 24 hours before I took a second dose and it made me feel jittery and my heart was racing. Tried to eat and drink something but it didn't help., Applies to: Sudafed Congestion (pseudoephedrine) Consumer information for this interaction is not currently available. MONITOR: Coadministration of two or more sympathomimetic agents may increase the risk of adverse effects such as nervousness, irritability, and increased heart rate. Central nervous system (CNS) stimulants, particularly ..., Brain Injury or Disease. Pressure that builds inside your brain after a head injury, stroke, or tumor can damage the muscles in your iris that normally make your pupils open and close. One or both ..., 5. You're dehydrated. "The most common cause of dry mouth is dehydration ," Dr. Esposito says. Fortunately, it's also the easiest to fix. "If you're not drinking enough water and you're ..., Fainting, blackouts and anxiety. Yes, this is typically referred to as a panic attack, and these can be fairly common on undiagnosed celiacs who still eat gluten. I had this symptom for years before being diagnosed. 10 hours ago - Scott Adams replied to Painful5 's topic in Related Issues & Disorders. 1., Pseudoephedrine is a safe and effective medication when used as directed. Along with its intended actions, it may cause some side effects. These may include nervousness, fast or pounding heartbeat, headache, or stomach upset. Drowsiness, however, is not generally considered a common side effect. The likelihood of experiencing drowsiness or any ..., The wake back to bed technique also requires waking up after five hours of sleep. With WBTB, you'll want to stay awake for about 30 to 120 minutes before returning to sleep. Keep a record of your dreams: Every morning, write down everything you remember about your dreams in a journal. You can also use a voice-recording device to log your ..., A leukotriene inhibitor is a prescription medication that blocks symptom-causing chemicals called leukotrienes. This oral medication relieves allergy signs and symptoms including nasal congestion, runny nose and sneezing. Only one type of this drug, montelukast (Singulair), is approved for treating hay fever., Most of the time, eye boogers are a normal part of waking up. They mean that your body is doing its job. But some conditions cause extra discharge, mucus, or irritation. Dry eye. Some people don’t produce enough tears. Or their tears aren’t made of the right balance of substances to keep their eyes moist., Pseudoephedrine, the active ingredient in Sudafed, is known to worsen symptoms of a condition known as benign prostatic hyperplasia because the medicine causes tightening of the muscles in the ..., Sudafed contains the active ingredient pseudoephedrine, which is a decongestant. It works by reducing the swelling and inflammation in the nasal passages, which can help relieve sinus congestion and improve breathing. Additionally, Sudafed can also reduce the production of mucus, which can further alleviate symptoms of bronchitis., 1. Dextromethorphan (Robitussin, Delsym) Dextromethorphan is the main ingredient in many over-the-counter (OTC) cough suppressants. If you've taken dextromethorphan, a urine test may show a false positive for PCP.. 2. Diphenhydramine (Benadryl) Diphenhydramine is an antihistamine that can help treat allergies, itching, and cold symptoms. Diphenhydramine may show up as a false positive for ..., 2. Keep decongestants on hand. Available in sprays, pills, syrups and even flavored powders, decongestants (like Sudafed) reduce the swelling of your nose's blood vessels, which helps to open up your airway. "Decongestants help with sinus congestion and pressure, as well as headaches," says Steinhilber. 3., You can take Tylenol pm tylenol and benedry. But DO NOT take the Tylenol together . Read More. I asked my pharmacist today because I have the same allergy issues - je said Lortadine OTC is perfectly safe (Claritin) just NO Sudafed or Psuedaphedrine (Claritin D or Allegra D). He also said my Flonase is safe., Fact-Checked. Up-to-Date. Key Takeaways. Caffeine promotes wakefulness by blocking adenosine, a sleep-inducing chemical. Sensitivity to caffeine varies among …, Speaking strictly for myself, I would try 90mg pseudoephedrine (I don't use sustained release caps) and 25 or 50mg diphenhydramine, if I needed to sleep with a clogged nose. I would expect it to not work and then wake up tired, but having slept for a few hours until the benadryl wore off. 2. Share. , Sudafed, containing pseudoephedrine, is a decongestant that helps relieve nasal congestion. It usually starts to work within 15 to 30 minutes after ingestion. Immediate-release Sudafed tablets provide relief for about 4 to 6 hours, while extended-release versions can last up to 12 to 24 hours., Mucinex can treat allergies in specific situations. Compared to medications like antihistamines, it doesn’t treat general allergy symptoms. Mucinex can only treat chest congestion or a cough caused by postnasal drip. If you have other symptoms — like a runny nose, watery eyes, or sneezing — Mucinex won’t make a difference., Common decongestants include the following: Sudafed ( Pseudoephedrine ) Sudafed PE ( Phenylephrine ) Afrin ( Oxymetazoline ) Nasal sprays work faster than oral decongestants. Don't use them for longer than recommended, though. They can irritate your nasal passages and make congestion worse.