Mucinex and nyquil at the same time

Mucinex DM (guaifenesin / dextromethorphan) is an over-the-counter medication that's used to relieve cough and loosen up mucus. It has two active ingredients: guaifenesin (an expectorant that clears chest congestion) and dextromethorphan (a cough suppressant that relieves cough). Mucinex DM (guaifenesin / dextromethorphan) is available as ...

Mucinex and nyquil at the same time. Mucinex can safely be taken with the original DayQuil Cold & Flu as there is no interaction between the medications. However, It is important to be aware that DayQuil is a brand name, and comes in a variety of additional brand formulations (e.g. DayQuil Severe), some of which contain the active ingredient in Mucinex (guaifenesin).

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Dextromethorphan comes as a liquid-filled capsule, a chewable tablet, a dissolving strip, a solution (liquid), an extended-release (long-acting) suspension (liquid), and a lozenge to take by mouth. It is usually taken every 4 to 12 hours as needed. Follow the directions on the package or prescription label carefully, and ask your doctor or ...A doctor has provided 1 answer. can i take benadryl (diphenhydramine) and nyquil together?: You can, but: Not recommended due to drug interactions. Both drugs inc. Using dextromethorphan together with promethazine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these ... Taking Claritin and Mucinex together may provide complementary benefits for managing allergy and cold symptoms. Claritin can help relieve allergy symptoms like sneezing, runny nose, and itching (1), while Mucinex can help loosen mucus and alleviate congestion associated with colds (2). By combining these medications, you may experience relief ...A doctor has provided 1 answer. Dr. Thomas Josa answered. Specializes in Allergy and Immunology. Yes: No problem taking both at the same time. Dr Fritz agreed. Answered 3/27/2020. 2k views. Thank.What is Mucinex Nightshift Sinus? Acetaminophen is a pain reliever and fever reducer. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant. Triprolidine is an antihistamine.. Mucinex Nightshift Sinus is a combination medicine used to treat headache, fever, body aches, cough, sore throat, runny or stuffy nose, sneezing, or sinus pressure caused by the flu or common cold.

Dayquil Cold and Flu relief actually contains the same cough suppressant as Mucinex DM (dextromethorphan). So, you would not take the two together.You can take plain Mucinex, which contains an expectorant and no cough suppressant, with Dayquil Cold and Flu/multi-symptom relief.Mucinex DM contains a larger amount of the cough suppressant (30 mg ... This can include diuretics, diabetes medications, and lithium. Interactions can result in low blood pressure, low blood sugar, and other signs and symptoms. Your healthcare provider and pharmacist can check for potential interactions. This can ensure you're taking lisinopril with other medications safely.Nightshift™ Cold & Flu. Maximum strength formula for nighttime cold & flu symptoms. Each 4-hour dose provides multi-symptom relief so you can have a better morning. Also available in Caplets. HSA/FSA eligible expense. 5.0. (3) Write a review.In this article, we'll explore whether it's safe to take Mucinex and Nyquil at the same time, and provide guidance on how to use these medications effectively for symptom relief. ... Both Mucinex and Nyquil may contain similar ingredients such as guaifenesin or dextromethorphan, so it is important to avoid doubling up on these ingredients to ...As per your description, it's advised to take NyQuil™ HBP that is free of decongestants for people with high blood pressure. As simple NyQuil contains Pseudoephedrine that constricts these blood vessels, which decreases drainage. But those same constricted vessels might also increase your blood pressure and heart rate.When you learn and maintain good time management skills, you’ll find freedom from deadline pressure and from When you learn and maintain good time management skills, you’ll find fr...Ketorolac can cause methotrexate to build up in your bloodstream. This may increase methotrexate levels. High levels of methotrexate can lead to serious side effects, including a low number of blood platelets. This effect on platelets may be more severe if you take ketorolac on the same day as methotrexate.If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Many times Mucinex Fast-Max Cold and Flu (acetaminophen, dextromethorphan, guaifenesin, phenylephrine caps & tabs) is taken on an as needed basis. Do not take more often than …

On the other hand, Mucinex contains guaifenesin, which helps loosen mucus and phlegm in the airways. It’s generally safe to take Nyquil and Mucinex together, as long as you follow the recommended dosages for each medication. However, it’s always wise to consult with your healthcare provider or pharmacist before combining any medications.Doubling Up on Active Ingredients. Some Mucinex products also contain other active ingredients besides guaifenesin. For instance, Mucinex DM has dextromethorphan, also found in NyQuil. Taking both medicines together could mean you're ingesting a double dose of this cough suppressant. Overdose of any medication can be harmful and lead to side ..."can i take antibiotics and cold medicine at the same time? i'm taking antibiotics for an ear infection, but have just come down with a really bad chest cold. can i take otc cold medicine, like mucinex (guaifenesin) at the same time? #nqlu" Answered by Dr. Eric Bouwens: Mucinex (guaifenesin) : Mucinex (guaifenesin) is compatible with all a...Tamsulosin Interactions. There are 293 drugs known to interact with tamsulosin, along with 4 disease interactions, and 2 alcohol/food interactions.Of the total drug interactions, 34 are major, 256 are moderate, and 3 are minor.

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Nyquil contains phenylephrine for decongestion, but it also contains ingredients to reduce fever and pain and suppress cough, which may still provide relief and ease your symptoms during the worst ...3. Reduced risk of complications: When used together, mucinex and nyquil can help to thin mucus and keep secretions flowing more freely. This can reduce the risk of serious complications, such as pneumonia, developing. 4. Better sleep: Nyquil can cause drowsiness, making it easier to fall asleep and stay asleep.Doxycycline Interactions. There are 207 drugs known to interact with doxycycline, along with 3 disease interactions, and 2 alcohol/food interactions.Of the total drug interactions, 22 are major, 180 are moderate, and 5 are minor.Ecommerce has entered deflation for the first time in over two years, according to the latest Adobe Digital Price Index (DPI). Ecommerce has entered deflation for the first time in...Pfizer Covid pills may be risky with other medications. In its fact sheet about Paxlovid, the FDA has published a detailed list of medications that may interact harmfully with ritonavir, including ...

NyQuil contains several sedating ingredients, including alcohol (10% by volume) and doxylamine, a first-generation antihistamine. NyQuil technically can be taken during the day, but remember that it will make you tired. Generally, it is best to only take it at night or if you plan on being home during the day resting.1 drugs are known to interact with benzonatate. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.Dec 19, 2017 ... In general, it is not recommended to take two different medications that contain the same ingredient, guaifenesin in this case. It may be more ...Official answer. by Drugs.com. The main difference is that DayQuil is a non-drowsy formula with the decongestant phenylephrine to help treat your cold or flu symptoms during the day, while many NyQuil products contain a sedating antihistamine and can help you sleep at night.Nyquil Cold & Flu (Acetaminophen, Chlorpheniramine, And Dextromethorphan) received an overall rating of 8 out of 10 stars from 2 reviews. See what others have said about Nyquil Col...The Available Preparations for Mucinex. Mucinex Extra Strength 12 Hour Extended Release - These are time-release bi-layer tablets. So, you need to take one pill for 12 hours. It comes in 1,200 mg guaifenesin extended-release preparation. Mucinex DM 12 Hour Extended Release - These are also time-release tablets. It is an expectorant and ...Mucinex D and NyQuil can be taken safely together (be careful if you have high blood pressure – talk to your doctor). Mucinex DM and NyQuil should not be taken together. Both medications have dextromethorphan, a cough suppressant.Aug 24, 2023 · Sudafed works as a decongestant. It helps to relieve stuffiness and sinus congestion or pressure due to the common cold or seasonal allergies. Mucinex is an expectorant. It loosens mucus and thins secretions in the lungs. This can help reduce chest congestion and make coughs more productive. You may opt to use Mucinex if your symptoms are ... The biggest difference between Mucinex D and NyQuil lies in their active ingredients and the manner, in which these medicines work to treat the symptoms. Mucinex D is used for treating chest congestion and the main ingredients in Mucinex are guaifenesin and pseudoephedrine. Guaifenesin is an expectorant and it helps in treating congestion by ...Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 1 Apr 2024), Cerner Multum™ …NyQuil, the 'night' version of DayQuil, contains doxylamine, a sedating antihistamine. Most people start to feel the effects, including feeling tired, about 30 to 60 minutes after taking a dose. Benzonatate also can make you feel tired, in about the same amount of time, although generally to a lesser extent than NyQuil.

A doctor has provided 1 answer. is it ok to take flonase and nyquil severe cold and flu at the same time?: : Yes. Flonase is a steroid nasal spray . Nyquil severe cold and flu c.

Yes, but no need: Nyquil contains acetaminophen, the active ingredient in tylenol. No need to double dose. Tylenol is very same, so lokiely no harm would come from it. Still, i would not take more medication than i need. Answered 3/7/2016.Also, because NyQuil contains acetaminophen (Tylenol), taking NyQuil with Tylenol Cold for example, is simply increasing your dosage of the medication. This is just another perfect breeding ground for an overdose.Yes you can.. Dr Basu : There is some risk of palpitation, high blood pressure with this combination. Dr Basu : However, occasional use should not cause any problem. Customer: she does have low thyroid and high blood pressure she has only mixed the meds once. Dr Basu : ok.Best cough and cold medicines for COVID-19: DayQuil, NyQuil, Mucinex, Sudafed, or Theraflu? Many over-the-counter medications can help relieve symptoms of the common cold, the flu, and COVID-19. ... Having both infections at the same time can raise your risk of severe symptoms and complications. This is especially true for older adults, ...A total of 446 drugs are known to interact with Benadryl . Benadryl is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis.Descriptions. Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.Taking NyQuil and Benzonatate together can pose potential risks due to drug interactions and the combination of active ingredients. Both of these meds can cause some similar side effects (1,2). NyQuil contains Doxylamine as one of its active ingredients, which is an antihistamine medication. Doxylamine can cause sedation and tiredness (3).Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or ...The study uses data from the FDA. It is based on esomeprazole magnesium and guaifenesin (the active ingredients of Nexium and Mucinex, respectively), and Nexium and Mucinex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

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Drowsiness. Dizziness. Dry mouth. It’s essential to be aware of these side effects and to avoid driving or operating heavy machinery while taking these medications. Taking Claritin with NyQuil in rare cases may cause more severe side effects. Difficulty breathing. Seizures or an Irregular heartbeat.Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 1 Apr 2024), Cerner Multum™ (updated 21 Apr 2024), ASHP (updated 10 Apr 2024) and others.Concerta disease interactions. There are 14 disease interactions with Concerta (methylphenidate) which include: agitation. cardiac disease. glaucoma. hypertension. psychiatric disorders. substance abuse. tics.Yes, Mucinex (guaifenesin) and Claritin can be taken together as there is no interaction between the two medications.I've written some additional information about both drugs below. Taking Claritin And Mucinex Together. Mucinex (guaifenesin) is an expectorant that helps loosen and thin mucus to make a cough more productive.There are several other products that guaifenesin is found in, in ...Key takeaways: Hydroxyzine (Vistaril) is a medication used for allergies, itching, and anxiety. It interacts with several medications and alcohol. Opioid pain medications and other antihistamines, such as diphenhydramine (Benadryl), interact with hydroxyzine. Combining them can cause severe drowsiness and raise the chance of accidental injuries.Adults—500 milligrams (mg) on Day 1 (the first day), taken as a single dose. Then, 250 mg on Day 2 through Day 5. Children 2 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 12 milligrams (mg) per kilogram (kg) of body weight once a day for 5 days.3. Reduced risk of complications: When used together, mucinex and nyquil can help to thin mucus and keep secretions flowing more freely. This can reduce the risk of serious complications, such as pneumonia, developing. 4. Better sleep: Nyquil can cause drowsiness, making it easier to fall asleep and stay asleep.Fever. "For fever, the two things we use more often than anything are acetaminophen and ibuprofen ," Vyas said. Tylenol is a common brand of acetaminophen; Advil and Motrin are common brands of ibuprofen. As with anything, it's important to check with a primary care provider on what you should and shouldn't be taking—for the common ...We would like to show you a description here but the site won't allow us.Taking too much Mucinex may cause nausea and vomiting, while taking too much Sudafed could cause dizziness or headache. In addition, both drugs should not be used for more than seven days unless otherwise directed by your doctor. Final thoughts. Together and separately, Mucinex and Sudafed can help manage your upper …Key takeaways: Hydroxyzine (Vistaril) is a medication used for allergies, itching, and anxiety. It interacts with several medications and alcohol. Opioid pain medications and other antihistamines, such as diphenhydramine (Benadryl), interact with hydroxyzine. Combining them can cause severe drowsiness and raise the chance of accidental injuries.Jul 6, 2023 · 6.25 mg of doxylamine. 5 mg of phenylephrine. The typical adult dosage of NyQuil Severe is 2 pills or 30 mL by mouth every 4 hours as needed. Don’t take more than 4 doses (8 pills or 120 mL) in 24 hours. It’s important to note that the VapoCOOL version contains 10% alcohol, whereas the other flavors are alcohol free. ….

Is it okay to take mucinex (guaifenesin) d and nyquil/dayquil together? A doctor has provided 1 answer. can i take mucinex (guaifenesin) with nyquil?: Yes: Most of the nyquil preparations do not have something to thin the.Like DayQuil, NyQuil contains the analgesic acetaminophen and the cough suppressant dextromethorphan. However, it does not have the nasal decongestant phenylephrine. NyQuil, the nighttime version ...Nasacort disease interactions. There are 4 disease interactions with Nasacort (triamcinolone nasal) which include: hyperadrenocorticism. infections. ocular herpes simplex. ocular toxicities.Yes you can will be very drowsy. Hello, you can take tramadol with nyquil, however they both may have the same dopey effect. It can slow your breathing down and even depress your pulse. Tramadol wasn't even considered a narcotic just a few years ago and its absolutely a mild narcotic, where you can take the nickel to help with your cough.Applies to: Vicks DayQuil Severe Cold & Flu (acetaminophen / dextromethorphan / guaifenesin / phenylephrine) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment.Can you take aleve (naproxen) and nyquil at the same time or something wil happen? A Verified Doctor answered. Rheumatology 54 years experience. Can take both: You may take both at ... Yes: Aleve is a NSAID or antiinflammatory, Mucinex is high dose Robitussin or Guaifenesin which is a mucolytic, and nyquil will have Benadryl (diphenhydramFlonase disease interactions. There are 5 disease interactions with Flonase (fluticasone nasal) which include: hyperadrenocorticism. infections. ocular herpes simplex. ocular toxicities. osteoporosis.Drowsiness. Dizziness. Dry mouth. It's essential to be aware of these side effects and to avoid driving or operating heavy machinery while taking these medications. Taking Claritin with NyQuil in rare cases may cause more severe side effects. Difficulty breathing. Seizures or an Irregular heartbeat. Mucinex and nyquil at the same time, Since immediate-release Tylenol products have a duration of action of around four to six hours, you should separate it from NyQuil by at least this amount of time. Extended-release Tylenol products (e.g. Tylenol arthritis) last around eight hours per dose. Therefore, waiting around eight hours after taking extended-release Tylenol before taking ..., A doctor has provided 1 answer. is it ok to take flonase and nyquil severe cold and flu at the same time?: : Yes. Flonase is a steroid nasal spray . Nyquil severe cold and flu c., Summary. Tylenol (acetaminophen) and prednisone are not known to interact with each other and should be safe to take at the recommended dosages. However, they can interact with other drugs ..., This means alcohol could make Ozempic not work as well as usual. (Ozempic is used to help manage blood sugar levels.) Alcohol could also increase your risk of low blood sugar. If you drink alcohol ..., Worse still, it tends to become more severe at bedtime. Unfortunately, oral nasal decongestants, such a Sudafed ( pseudoephedrine) and Sudafed PE ( phenylephrine), have stimulating effects for many individuals, and therefore may not be an option for you at bedtime. In fact, a variety of CNS (central nervous system) side effects …, Yes, you can take Sudafed with NyQuil, but both medications should have a bit of a dosing gap. Sudafed is a decongestant containing pseudoephedrine, whereas NyQuil is a multi-ingredient medication containing acetaminophen, dextromethorphan and doxylamine. NyQuil does not work for nasal congestion (1,2). Sudafed is used to provide temporary ..., On the other hand, Nyquil is a combination medication that typically includes ingredients like acetaminophen for pain relief, dextromethorphan as a cough suppressant, doxylamine succinate as an antihistamine for sneezing and runny nose, and sometimes phenylephrine as a decongestant. Can You Take Mucinex and Nyquil At The Same Time, NyQuil Severe Cold and Flu caplets and liquid in berry and original ( gluten-free) (acetaminophen 325 mg, dextromethorphan HBr 10 mg, doxylamine succinate 6.25 mg, and phenylephrine HCl 5 mg) ( note that this product is branded "NyQuil Complete" in Canada, where it's also gluten-free), Jan 8, 2022 · NyQuil, the 'night' version of DayQuil, contains doxylamine, a sedating antihistamine. Most people start to feel the effects, including feeling tired, about 30 to 60 minutes after taking a dose. Benzonatate also can make you feel tired, in about the same amount of time, although generally to a lesser extent than NyQuil. , Dec 27, 2012 ... ... NyQuil for treatment of cold symptoms. Case ... Thus, he started taking OTC NyQuil ... He was admitted to the intensive care unit, at which time his ..., As of 2015, Mucinex, which is guaifenesin, has no known drug interactions, according to Drugs.com. However, individuals should consult their doctors or pharmacists when taking this..., For nasal dosage form (Astelin® spray): For treatment of seasonal allergic rhinitis: Adults and children 12 years of age and older—1 or 2 sprays in each nostril 2 times a day, or 2 sprays in each nostril once a day. Each spray contains 137 or 205.5 micrograms (mcg) of azelastine. Children 6 to 11 years of age—1 spray in each nostril 2 ..., I've been coughing up a lot of phlegm and mucous and was hoping that it would be alright to mix these two together. Archived post. New comments cannot be posted and votes cannot be cast. Yes, you can take both, but something with an expectorant (guaifenesin/Mucinex) would be more helpful with your phlegm than NyQuil., As with any medication, there may be side effects that occur when taking Paxlovid. The most common reported side effects are altered sense of taste, diarrhea, high blood pressure, and sore or achy muscles. Patients should reach out to their doctor or pharmacist immediately if they experience loss of appetite, yellowing of skin or eyes, itchy ..., Is it okay to take mucinex (guaifenesin) d and nyquil/dayquil together? A doctor has provided 1 answer. can i take mucinex (guaifenesin) with nyquil?: Yes: Most of the nyquil preparations do not have something to thin the., Applies to: Mucinex DM (dextromethorphan / guaifenesin) and Vicks Nyquil Cough (dextromethorphan / doxylamine) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment., Mucinex, as an expectorant, can also contribute to dryness in the mouth and throat. When taken together, the risk of experiencing dry mouth and throat may be heightened. It is important to stay hydrated while using these medications and consider using lozenges or sugar-free gum to alleviate any discomfort caused by dryness., The Available Preparations for Mucinex. Mucinex Extra Strength 12 Hour Extended Release – These are time-release bi-layer tablets. So, you need to take one pill for 12 hours. It comes in 1,200 mg guaifenesin extended-release preparation. Mucinex DM 12 Hour Extended Release – These are also time-release tablets. It is an expectorant and ..., So if you've ever wondered whether it's safe to take Motrin and Nyquil at the same time, keep reading to find out more. Motrin, also known as ibuprofen, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. On the other hand, Nyquil is a popular over-the-counter cold and flu ..., Can I take a decongestant pill and nasal spray at the same time? Consumer Reports News: April 23, 2012 12:08 PM. When I use an over-the-counter decongestant nasal spray, like Afrin, can I also..., Taking Aleve and Tylenol at the same time is safe. Yes, Aleve and Tylenol are generally safe to take at the same time. However, taking them at different times is often more effective. A person ..., Applies to: Mucinex DM (dextromethorphan / guaifenesin) and Vicks Nyquil Cough (dextromethorphan / doxylamine) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. , Extended-release tablets. Regular strength (Mucinex DM and generic): Each tablet contains 600 mg of guaifenesin and 30 mg of dextromethorphan. People 12 years and older: The typical dose is 1 or 2 tablets by mouth every 12 hours. Don't take more than 4 tablets in a 24-hour period. Children under age 12: Don't use., NyQuil gives relief in the symptoms of common cold and flu, including a cough, fever, nasal congestion, body aches, headache, sneezing, and runny nose. The …, Mucinex D is (guaifenesin and pseudoephedrine) is an expectorant/nasal decongestant combination, and Mucinex DM (guaifenesin and dextromethorphan) is an expectorant/cough suppressant combination. Mucinex D and Mucinex DM both contain the expectorant guaifenesin (which is contained as a single ingredient in Mucinex).. …, Compare Mucinex DM vs. Nyquil. Head-to-head comparisons of medication uses, side effects, warnings, and more. Mucinex dm (guaifenesin / dextromethorphan) Nyquil cold and flu. Summary. Mucinex DM (guaifenesin / dextromethorphan) is an over-the-counter medication that's used to relieve cough and loosen up mucus., Mucinex is an orally administered expectorant approved by the FDA to help loosen thin mucus in the lungs and airways to make it easier to cough out the mucus. Guaifenesin is the single active ingredient in Mucinex. Mucinex extended-release (ER) tablet is approved for use in adults and children 12 years and older., Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 1 Apr 2024), Cerner Multum™ (updated 21 Apr 2024), ASHP (updated 10 Apr 2024) and others., Guaifenesin is an expectorant sold under the brand name Mucinex, Bidex, Organidin, Robafen, and others. Guaifenesin reduces the viscosity of mucus so it can be easily coughed up. Guaifenesin is found in many multi-symptom cold & cough medicines, including: Coricidin HBP Day & Night Multi-Symptom Cold. Robitussin DM., Cyclobenzaprine and alcohol. Alcohol is a CNS depressant, like cyclobenzaprine. Combining alcohol with cyclobenzaprine can result in the complications described above such as impairment and extreme sedation—and in some cases, it can cause slowed breathing, coma, or even death. Avoid alcohol while taking cyclobenzaprine., 1 drugs are known to interact with benzonatate. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment., Answer. Yes, ZzzQuil and Mucinex are safe to take together. There is no known drug interaction between the two. ZzzQuil contains the drug diphenhydramine. Diphenhydramine isn't exclusive to NyQuil as it is also the active ingredient in several other products, including Benadryl. It is a 'first-generation' antihistamine, and while it will help ..., Warnings. One ingredient in this product is acetaminophen. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Adults should not take more than 4000 milligrams (4 grams ...